Lymphangioleiomyomatosis and SZ alpha(1)-antitrypsin disease: a unique combination?

Chan, Andrew L; Kwack, Sunye; Jones, Kirk D; Glassberg, Marilyn K; Gherman, Charles R · Chest · 2003

case_report · Level V

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Abstract

We describe a case of a 37-year-old female ex-smoker with lymphangioleiomyomatosis and SZ alpha(1)-antitrypsin disease who underwent successful bilateral sequential lung transplantation. While this disease combination has not been described previously, we recommend vigilance for the possibility of such combinations in patients with chronic lung disease. The possible mechanisms of interaction resulting from both disease processes are discussed.

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