Nuclear receptors: a rendezvous for chromatin remodeling factors.
review · Level V
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Abstract
Nuclear receptors (NRs) are a large family of ligand-induced transcription factors that include the vitamin D receptor. The recent discovery of WINAC, a novel ATP-dependent chromatin remodeling complex, has shed new light on the molecular mechanisms by which the vitamin D receptor controls gene expression with unexpected clinical implications.
Medical subject headings
- Chromatin
- Receptors, Cytoplasmic and Nuclear