Recurrent delayed brain hemorrhage over years after irradiation and chemotherapy for astrocytoma.

Hillemanns, Andreas; Kortmann, Rolf-Dieter; Herrlinger, Ulrich; Skalej, Martin; Krapf, Hilmar · Eur Radiol · 2003

case_report · Level V

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Abstract

We report on an adult patient with a right frontal astrocytoma, classification WHO II, who suffered from radionecrosis 3.5 years after surgery and combined radio- and chemotherapy. Beginning 8 years after initial diagnosis, repeated episodes of bilateral cerebral hemorrhage and cavitation occurred. This case description emphasizes the possibility of repeated hemorrhage as a delayed reaction to brain irradiation and chemotherapy.

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