Language lateralization by Wada test and fMRI in 100 patients with epilepsy.

Woermann, F G; Jokeit, H; Luerding, R; Freitag, H; Schulz, R; Guertler, S; Okujava, M; Wolf, P et al. · Neurology · 2003

cross_sectional · Level IV

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Abstract

Comparing the determination of language dominance using fMRI with results of the Wada test in 100 patients with different localization-related epilepsies, the authors found 91% concordance between both tests. The overall rate of false categorization by fMRI was 9%, ranging from 3% in left-sided temporal lobe epilepsy (TLE) to 25% in left-sided extratemporal epilepsy. Language fMRI might reduce the necessity of the Wada test for language lateralization, especially in TLE.

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