Case report 714. Postirradiation osteosarcoma after radiation of metastatic skeletal lesion.
case_report · Level V
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- Record sourced from PubMed, PMID 1314427.
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Abstract
Two cases of postirradiation osteosarcoma are presented--one in a 76-year-old woman with breast carcinoma and subsequent osteosarcoma after radiation therapy for a metastatic lesion in the right tibia, and the other in a 16-year-old girl with hepatocellular carcinoma metastatic to the left tibia and osteosarcoma after radiation therapy to that bone. Microscopically, both cases were high-grade spindle cell lesions with osteoid production. Both patients fared poorly. This is a rare complication of radiation therapy.
Medical subject headings
- Bone Neoplasms
- Neoplasms, Radiation-Induced
- Neoplasms, Second Primary
- Osteosarcoma
- Tibia
Anatomy
- tibia