A novel reciprocal chromosome translocation t(11;22)(p13;q12) in an intraabdominal desmoplastic small round-cell tumor.
case_report · Level V
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Abstract
We report an intraabdominal desmoplastic small round-cell tumor that contains a novel reciprocal chromosome translocation t(11;22)(p13;q12). The tumor showed a reciprocal chromosome translocation which is different from the (11;22)(q24;q12) translocations seen in Ewing's and other small-cell tumors but affects the same break-point on chromosome 22(q12). This reciprocal chromosome translocation may prove to be a marker for intraabdominal desmoplastic small round-cell tumors.
Medical subject headings
- Abdominal Neoplasms
- Carcinoma, Small Cell
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 22
- Translocation, Genetic