Prognostic importance of human papillomavirus type 16 DNA in cervical cancer.
case_series · Level IV
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Abstract
Human papillomavirus (HPV) type 16 DNA is frequent in invasive cervical cancers. Among 43 patients with invasive cervical cancer, HPV-16-positive tumors spread to the parametrial and pelvic lymph nodes significantly more often than did HPV-16-negative tumors (P less than 0.05). Demonstration of HPV-16 DNA in invasive cervical cancers may be an additional prognostic factor for this disease.
Medical subject headings
- DNA, Viral
- Papillomaviridae
- Tumor Virus Infections
- Uterine Cervical Neoplasms