Intracellular synthesis of varicella-zoster virus.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 1320653.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Varicella-zoster virus, a reclusive alpha-herpesvirus, can be isolated and propagated in a limited number of human cell lines. Under in vitro conditions, the virus is strongly cell-associated and, therefore, difficult to recover in a truly cell-free state. The general replication cycle includes the three phases called immediate early, early, and late. An example of an early viral protein is a putative protein kinase called open reading frame (ORF) 47. An example of a late protein is the preponderant viral glycoprotein (ORF 68) designated VZV gpI.
Medical subject headings
- Herpesvirus 3, Human
- Viral Proteins
- Virus Replication