Alpha-adrenergic bronchoprovocation in neonates with bronchopulmonary dysplasia.
case_control · Level III
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Abstract
Ophthalmic administration of phenylephrine caused decreased pulmonary compliance, tidal volume, and peak airflow values in infants with bronchopulmonary dysplasia but not in control infants. The alpha-adrenergic effects of phenylephrine may aggravate the bronchospastic component of bronchopulmonary dysplasia.
Medical subject headings
- Bronchopulmonary Dysplasia
- Phenylephrine
- Receptors, Adrenergic, alpha
- Respiratory Mechanics