Cloning and expression of chicken erythrocyte transglutaminase.
basic_science · Level V
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- Record sourced from PubMed, PMID 1357669.
- Also identified by PMC identifier 50221.
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Abstract
We report the sequences of cDNAs encoding chicken erythrocyte transglutaminase (EC 2.3.2.13). The complete mRNA consists of 3345/3349 nucleotides and predicts a single open reading frame. Nine peptide sequences derived from partial digests of the isolated protein agreed with the corresponding translation of the open reading frame. Approximately 60% identities between the avian protein and three related mammalian enzymes were found. Chicken erythrocyte transglutaminase mRNA is most abundant in red blood cells and kidney, and it accumulates during erythroid cell differentiation.
Medical subject headings
- Erythrocytes
- Transglutaminases