The California Maternal Serum alpha-Fetoprotein Screening Program: the role of ultrasonography in the detection of spina bifida.

Platt, L D; Feuchtbaum, L; Filly, R; Lustig, L; Simon, M; Cunningham, G C · Am J Obstet Gynecol · 1992

case_series · Level IV

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Abstract

Between January 1988 and June 1990, 161 cases of open spina bifida were identified by the California Maternal Serum alpha-Fetoprotein Screening Program. Eight percent of these cases were not diagnosed by an initial ultrasonographic evaluation. Three defects were not recognized until birth. Ultrasonography is inadequate to identify all cases of open spina bifida.

Medical subject headings