Clonazepam treatment of myoclonic contractions associated with high-dose opioids: case report.

Eisele, John H; Grigsby, Eric J; Dea, Gilland · Pain · 1992

case_report · Level V

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Abstract

A 30-year-old man with chronic abdominal pain was treated with high doses of hydromorphone intravenously and developed severe and frequent myoclonic contractions. Several medications including lorazepam failed to control the contractions; however, clonazepam in normal doses reduced the myoclonus dramatically.

Medical subject headings