Impression cytology of conjunctival melanosis and melanoma.
case_report · Level V
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- Record sourced from PubMed, PMID 1390485.
- Also identified by PMC identifier 504226.
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Abstract
Impression cytology using cellulose acetate paper has been used in various ocular surface disorders as a simple non-invasive diagnostic test. To assess its value in differentiating melanocytic tumours, 24 patients with a range of pigmented lesions of the conjunctiva were examined using this technique. Cytological and histological diagnoses were compared in 23 cases. In 73% of cases impression cytology predicted the histological diagnosis by detection of superficial atypical melanocytes and their proportion relative to benign epithelial cells. This pilot study shows impression cytology to be a useful diagnostic aid in the differentiation of pigmented tumours of the bulbar conjunctiva.
Medical subject headings
- Conjunctiva
- Conjunctival Neoplasms
- Melanoma
- Melanosis