Prenatal exclusion of Norrie's disease.
Level V
Where this comes from
- Record sourced from PubMed, PMID 1390533.
- Also identified by PMC identifier 504324.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We report on the use of DNA marker probes and linkage analysis to exclude Norrie's disease in the male fetus of a high risk carrier. There are no clinical markers in females carrying the Norrie's disease gene; thus DNA linkage analysis is an essential technique in the management of families 'at-risk' for this severe ophthalmic disease. The principles of DNA linkage are discussed.
Medical subject headings
- Blindness
- Fetal Diseases
- Prenatal Diagnosis