Hypertension, left ventricular hypertrophy, ventricular arrhythmias and sudden death.

Abstract

LVH is a common sequela of arterial hypertension; it increases the risk of sudden death and other cardiovascular morbidity and mortality independent of arterial pressure and has been associated with ventricular arrhythmias. Electrophysiological studies suggest a connection between ventricular arrhythmias in patients with LVH and sudden death. LVH can be reduced by specific antihypertensive therapy, although not all drugs are equipotent in this regard. A reduction in LVH has been shown to diminish ventricular ectopy. Preliminary findings suggest that a reduction of LVH and associated arrhythmias may reduce its inherent cardiovascular risk.