Antibodies to lipid A in pauciarticular juvenile arthritis: clinical studies.
case_series · Level IV
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- Record sourced from PubMed, PMID 1404135.
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Abstract
IgG antibodies to monophosphoryl lipid A (MPL) are more concentrated in synovial fluids than in the blood of children with pauciarticular juvenile arthritis. Correlations between IgG anti-MPL levels and numbers of inflamed joints were highly significant in 2 of 10 patients followed for 8 years and suggestive in 2 patients followed for shorter periods. A fifth patient had a correlation between IgM anti-MPL and joint count.
Medical subject headings
- Antibodies
- Arthritis, Juvenile
- Lipid A