Amyloidoma of the CNS. I. Clinical and pathologic study.

Cohen, M; Lanska, D; Roessmann, U; Karaman, B; Ganz, E; Whitehouse, P; Gambetti, P · Neurology · 1992

case_report · Level V

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Abstract

We report a 32-year-old man with a 4-year history of headaches, seizures, and dementia secondary to multifocal amyloidomas in the white matter. Immunohistochemical and electron microscopic analyses suggest that the amyloidomas resulted from processing of plasma-cell-derived amyloidogenic protein by microglial cells.

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