Recombinant erythropoietin as treatment for the late hyporegenerative anemia of Rh hemolytic disease.
case_report · Level V
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Abstract
Infants with Rh hemolytic disease can develop a "late" anemia characterized by low serum concentrations of erythropoietin but erythroid progenitors that remain highly erythropoietin-responsive. Erythropoietin administration was evaluated in two patients as an alternative to transfusion. Reticulocyte counts increased after 5 days of treatment, and hematocrits increased after 10 days. Neither patient received erythrocyte transfusions following erythropoietin therapy.
Medical subject headings
- Anemia, Hemolytic
- Erythropoietin
- Rh Isoimmunization