Radiation-induced optic neuropathy: correlation of MR imaging and radiation dosimetry.

Young, W C; Thornton, A F; Gebarski, S S; Cornblath, W T · Radiology · 1992

case_report · Level V

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Abstract

The authors performed topographic correlation of dosimetric measurements with contrast medium-enhanced magnetic resonance (MR) imaging signal aberration in two cases of radiation optic neuropathy. The region of pathologic contrast enhancement in the optic nerve and chiasm had received 55-62 Gy, which supports the theory that the risk of injury to the optic nerve and chiasm increases steeply with radiation doses above the tolerance level of 50-55 Gy.

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