Cell biology. An age of instability.
Level V
Where this comes from
- Record sourced from PubMed, PMID 14512612.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
It is well established that as we age our cancer risk increases dramatically. As Sinclair explains in his Perspective, the link between cancer and aging is now solidified by new work in budding yeast (McMurray and Gottschling). As yeast cells age there is a marked increase in their genetic instability (a hallmark of cancer), which is independent of the mechanism that determines their life-span.
Medical subject headings
- Aging
- Cellular Senescence
- Genes, Fungal
- Mutation
- Saccharomyces cerevisiae