Atrophic dermatofibrosarcoma protuberans: case report, review, and proposed molecular mechanisms.
case_report · Level V
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Abstract
We report a case of atrophic dermatofibrosarcoma protuberans, an uncommon clinical variant. We discuss molecular and genetic mechanisms of dermatofibrosarcoma protuberans tumorigenesis, review the literature on atrophic dermatofibrosarcoma protuberans, and pose a molecular mechanism for the atrophic variant's phenotype. We also describe using Mohs micrographic excision with CD34 immunostains on the frozen sections to definitively treat the tumor.
Medical subject headings
- Dermatofibrosarcoma
- Skin Neoplasms