Estrogen receptor expression in vulvar vestibulitis syndrome.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 14520218.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A pilot study was performed to investigate the relationship between vulvar vestibulitis syndrome and estrogen receptor expression. Women with a diagnosis of vulvar vestibulitis syndrome had tissue samples taken for vulvar estrogen receptor-alpha expression and this was compared with a control group. The study group showed a significant decrease in estrogen receptor expression, and 50% of the samples did not exhibit any receptor expression. There appears to be a subgroup of women with vulvar vestibulitis syndrome who exhibit abnormal estrogen receptor-alpha expression. This may be helpful in explaining why some women are resistant to medical treatment and may allow treatment to be prescribed more effectively.
Medical subject headings
- Pain
- Receptors, Estrogen
- Vulvitis