A polo match for Plk1.
editorial · Level V
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Abstract
New work by Elia et al. in this issue of Cell reveals the molecular basis of phosphopeptide recognition by the polo domain and the domain's dual function to promote substrate recognition by targeting the kinase to subcellular structures and to autoregulate the adjacent protein kinase catalytic domain.
Medical subject headings
- Phosphopeptides
- Protein Kinases