Circadian rhythms. Liver regeneration clocks on.
editorial · Level V
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- Record sourced from PubMed, PMID 14551421.
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Abstract
In some simple protozoans and unicellular algae, the cell cycle clock is strongly influenced by the circadian clock, such that mitotic cell division takes place only at certain times of the day. Now, as Schibler reports in his Perspective, new work on regenerating liver cells in mice (Matsuo et al.) reveals that the cell cycle clock of mammalian cells is also under the yoke of the master circadian oscillator.
Medical subject headings
- Biological Clocks
- Cell Cycle Proteins
- Cell Division
- Circadian Rhythm
- Drosophila Proteins
- Eye Proteins
- Hepatocytes
- Liver Regeneration
- Photoreceptor Cells, Invertebrate