Tetracyclines for treating multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia.
case_series · Level IV
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Abstract
To report the use of tetracyclines for the treatment of multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia (VAP). Observational case series. . The Presley Regional Trauma Center located within the Regional Medical Center, Memphis, Tennessee, USA. Seven critically ill trauma patients with VAP caused by A. baumannii isolates that were resistant to all antibiotics tested except for doxycycline or minocycline. Patients were treated with IV doxycycline or minocycline for an average of 13.5 (range 9-20) days. Doxycycline or minocycline was successful in six of seven patients. Doxycycline or minocycline may be effective for treating multidrug-resistant A. baumannii VAP.
Medical subject headings
- Acinetobacter Infections
- Acinetobacter baumannii
- Anti-Bacterial Agents
- Cross Infection
- Doxycycline
- Minocycline
- Pneumonia, Bacterial
- Respiration, Artificial