Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD.
case_control · Level III
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Abstract
Mutations in DJ-1 are a cause of autosomal recessive parkinsonism. Polymorphism of genes implicated in hereditary forms of parkinsonism may be a predisposing factor in sporadic Parkinson's disease (PD). The authors analyzed whether a polymorphism (g.168_185del) within exon 1 of DJ-1 contributes to the risk of sporadic PD in a Finnish case-control series. This gene does not play a major role in the genetic predisposition to PD in this population.
Medical subject headings
- Oncogene Proteins
- Parkinson Disease
- Polymorphism, Genetic