Unusual bilateral renal histiocytosis. Extranodal variant of Rosai-Dorfman disease.

Afzal, M; Baez-Giangreco, A; al Jaser, A N; Onuora, V C · Arch Pathol Lab Med · 1992

case_report · Level V

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Abstract

A 37-year-old Bangladeshi presented with large bilateral masses involving the hilus of the kidneys. No lymphadenopathy was noted. Nephrectomy was performed. Histopathologically, it revealed a lymphohistiocytic and plasma cell inflammatory tumoral proliferation with characteristic lymphophagocytosis by the S100-positive-CD1-negative histiocytes. Extranodal presentation of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) should be entertained in the differential diagnosis of bilateral masses involving the kidneys.

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