Linezolid-associated toxic optic neuropathy: a report of 2 cases.
case_report · Level V
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- Record sourced from PubMed, PMID 14583875.
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Abstract
We describe 2 cases in which the prolonged use of linezolid to treat complicated methicillin-resistant Staphylococcus aureus infections was followed by acutely developed blurred vision and progressive loss of vision and color perception during the ensuing few weeks. Both patients received a diagnosis of toxic optic neuropathy, and linezolid therapy was stopped. The patients experienced an initial rapid partial improvement and a subsequent gradual, almost complete, recovery over many months.
Medical subject headings
- Acetamides
- Anti-Infective Agents
- Optic Nerve Diseases
- Oxazolidinones