Dually infected (HSV-1/VZV) single neurons in human trigeminal ganglia.

Theil, Diethilde; Paripovic, Igor; Derfuss, Tobias; Herberger, Simone; Strupp, Michael; Arbusow, Viktor; Brandt, Thomas · Ann Neurol · 2003

basic_science · Level V

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Abstract

Human trigeminal ganglia were tested by double fluorescence in situ hybridization for the presence and distribution of herpes simplex virus type 1 (HSV-1) and varicella-zoster virus (VZV) latency. Latency transcripts of both viruses were detected in common areas within the ganglia. Also, a few single neurons were shown to harbor HSV-1 and VZV together.

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