Successful twin pregnancy in panhypopituitarism caused by suprasellar germinoma.

Abstract

Pregnancy in a woman with hypopituitarism from a suprasellar germinoma is rare. A 27-year-old woman presented with panhypopituitarism from a suprasellar germinoma. She had diabetes insipidus, hypothyroidism, adrenal cortex dysfunction, and hypogonadotropic ovarian failure. When treated with thyroxin, cortisol, antidiuretic hormone, human menopausal gonadotropin, and human chorionic gonadotropin, she conceived and gave birth to healthy twins. Hormonal replacement therapy and ovulation induction resulted in a successful pregnancy in a woman with panhypopituitarism.