Human cellular inflammation in the pathology of acute cerebral ischaemia.

Price, C J S; Warburton, E A; Menon, D K · J Neurol Neurosurg Psychiatry · 2003

review · Level V

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Abstract

Leucocytes form important effector pathways for inflammation. This article reviews the clinical evidence for the presence of a cellular inflammatory response in cerebral ischaemia, and attempts to define its temporal profile and spatial distribution. The processes involved in recruitment and activation of leucocytes in this context are addressed, and the successes and failures of interventions aimed at these processes discussed.

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