Brucellosis with nephrotic syndrome, nephritis and IgA nephropathy.
case_report · Level V
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- Record sourced from PubMed, PMID 1461859.
- Also identified by PMC identifier 2399514.
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Abstract
A patient with systemic brucellosis due to Brucella melitensis had severe renal involvement. Clinical features included hypertension, macroscopic haematuria, massive proteinuria of 10 g per 24 hours and azotaemia. Following treatment with antibiotics, the azotaemia resolved and proteinuria decreased to less than 0.5 g per 24 hours, but microscopic haematuria and hypertension persisted. Renal biopsy during recovery revealed IgA nephropathy with minimal mesangial changes, suggesting a causal relation between brucellosis and IgA nephropathy with a reversible nephrotic syndrome.
Medical subject headings
- Brucellosis
- Glomerulonephritis, IGA
- Nephrotic Syndrome