Angiogenesis in nervous system disorders.
review · Level V
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- Record sourced from PubMed, PMID 14633302.
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Abstract
Angiogenesis is a crucial requirement for embryonal development and new vessel formation during adult life. Various disease processes such as cancer, ischemia, vascular malformations, and inflammatory processes also depend on pathological angiogenesis. A better understanding of the complex and coordinated interactions among various angiogenic pathways involved in pathological angiogenesis is necessary to improve our therapeutic approaches to the various disease processes observed in the central nervous system. This review summarizes the current understanding of the role of principal angiogenic factors relevant to neurosurgical abnormalities.
Medical subject headings
- Neovascularization, Pathologic
- Nervous System
- Nervous System Diseases