Venous leg ulcers: a prognostic index to predict time to healing.

Abstract

To evaluate the prognostic factors in uncomplicated venous leg ulcer healing. Randomised parallel group controlled trial with subjects stratified by initial ulcer diameter and four months' maximum duration of follow up. Assessment at Northwick Park Hospital vascular unit with community based treatment. 200 patients with clinical and objective evidence of uncomplicated venous leg ulceration and an initial ulcer diameter > 2 cm. Time to complete healing of the ulcer. In the presence of graduated compression healing occurred more rapidly in patients with a smaller initial ulcer area (relative risk of healing 1.92 associated with halving of ulcer area (95% confidence interval 1.58 to 2.33)), shorter duration of ulceration (relative risk 1.35 associated with halving duration (1.17 to 1.56)), younger age (relative risk 1.34 associated with 10 year decrease (1.12 to 1.59)), and no deep vein involvement (relative risk 1.8 (1.19 to 2.78)). These prognostic factors used in a simple scoring system predict time to healing.