Rad53: a controller ensuring the fine-tuning of histone levels.

Quivy, Jean-Pierre; Almouzni, Geneviève · Cell · 2003

basic_science · Level V

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Abstract

Checkpoint proteins are activated in response to genotoxic insults or replication stress to maintain genome integrity. Their function is believed to depend largely on the detection of the DNA damage or defects occurring during replication fork progression.

Medical subject headings