Association between folic acid food fortification and congenital orofacial clefts.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 14657833.
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Abstract
By January 1998, most of Canada's cereal grain products were being fortified with folic acid. Among 336963 women who underwent antenatal maternal serum screening, the prevalence of orofacial clefts did not change from before (1.15 per 1000) to after (1.21 per 1000) food fortification (prevalence ratio, 1.06; 95% confidence interval, 0.86-1.30).
Medical subject headings
- Cleft Lip
- Cleft Palate
- Folic Acid
- Food, Fortified
- Hematinics