Etomidate shortens the onset time of neuromuscular block.

Gill, R S; Scott, R P · Br J Anaesth · 1992

rct · Level II

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Abstract

We have studied 30 healthy patients allocated randomly to receive thiopentone, propofol or etomidate in equipotent doses followed by vecuronium 0.1 mg kg-1. Haemodynamic variables and time to 100% neuromuscular block were measured. The patients receiving etomidate had a significantly shorter onset time of neuromuscular block compared with those receiving the two other i.v. induction agents. There was a significant negative correlation between onset time of neuromuscular block and the maximum percent change in mean arterial pressure.

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