Noninflammatory bullae associated with epsilon-aminocaproic acid infusion.

Brooke, C P; Spiers, E M; Omura, E F · J Am Acad Dermatol · 1992

case_report · Level V

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Abstract

Three patients who had cardiac surgery developed a transient, noninflammatory subepidermal bullous eruption on the legs after epsilon-aminocaproic acid infusion. Fibrin thrombi were demonstrated in papillary dermal vessels. The use of epsilon-aminocaproic acid as an antifibrinolytic agent may predispose patients to cutaneous vascular thromboses.

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