Necrobiotic xanthogranuloma in a human T-lymphotropic virus type 1 carrier.

Nishimura, M; Takano-Nishimura, Y; Yano, I; Hayashi, N; Toshitani, S · J Am Acad Dermatol · 1992

case_report · Level V

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Abstract

A 67-year-old man who had necrobiotic xanthogranuloma associated with paraproteinemia is described. He was a human T-lymphotropic virus type 1 (HTLV-1) carrier who had a high titer of circulating anti-HTLV-1 antibodies and neurologic abnormalities that suggested HTLV-1-associated myelopathy. The patient's necrobiotic xanthogranuloma and neurologic symptoms improved after he received four 5-day courses of melphalan, 2 mg/day, and prednisolone, 20 mg/day, at 4-week intervals.

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