TM or not TM: transmembrane protein prediction with low false positive rate using DAS-TMfilter.
other · Level V
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Abstract
Web-based servers implementing the DAS-TMfilter algorithm have been launched at three mirror sites and their usage is described. The underlying computer program is an upgraded and modified version of the DAS-prediction method. The new server is (approximately 1 among 100 unrelated queries) while the high efficiency of the original algorithm locating TM segments in queries is preserved (sensitivity of approximately 95% among documented proteins with helical TM regions). The server operates at three mirror sites: http://mendel.imp.univie.ac.at/sat/DAS/DAS.html, http://wooster.bip.bham.ac.uk/DAS.html and http://www.enzim.hu/DAS/DAS.html. The program is available on request.
Medical subject headings
- Algorithms
- Membrane Proteins
- Sequence Alignment
- Sequence Analysis, Protein
- Sequence Homology, Amino Acid