Old drugs, new tricks: using genetically sensitized yeast to reveal drug targets.
review · Level V
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- Record sourced from PubMed, PMID 14718160.
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Abstract
A study in this issue of Cell illustrates the power of applying genomic approaches with model systems to characterize the biological activity of small molecules and to identify their cellular targets, which can clarify the mode of action of human therapeutics.
Medical subject headings
- Drug Delivery Systems
- Drug Design
- Drug Evaluation, Preclinical
- Yeasts