Antigliadin antibodies in Huntington's disease.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 14718716.
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Abstract
The relevance of gluten sensitivity in sporadic and hereditary ataxia pathogenesis is unclear. The authors found high antigliadin antibody titers in 23 of 52 (44%) patients with Huntington's disease (HD), suggesting a previously unrecognized association between HD and gluten sensitivity. The results further question "gluten ataxia" as a distinct disease entity and raise the possibility that antigliadin antibodies in ataxia and other neurodegenerative diseases may be an epiphenomenon, the mechanisms of which remain to be investigated.
Medical subject headings
- Antibodies
- Gliadin
- Huntington Disease
- Immunoglobulin A
- Immunoglobulin G