Recurrent transverse myelitis associates with anti-Ro (SSA) autoantibodies.

Hummers, L K; Krishnan, C; Casciola-Rosen, L; Rosen, A; Morris, S; Mahoney, J A; Kerr, D A; Wigley, F M · Neurology · 2004

case_control · Level III

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Abstract

Transverse myelitis (TM) is an idiopathic inflammatory disorder of the spinal cord. The authors observed cases of recurrent TM in patients where anti-Ro (SSA) antibodies were present and therefore performed a case-control study to examine the frequency of anti-Ro autoantibodies in patients with recurrent TM and control subjects. Antibodies to 52-kd Ro were demonstrated in 77% of cases (10/13) compared with only 33% of control subjects (4/12).

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