Hepatic fibrosis and survival in biliary atresia.

Weerasooriya, Viraine S; White, Frances V; Shepherd, Ross W · J Pediatr · 2004

Level V

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Abstract

In biliary atresia, progression of hepatic fibrosis before the Kasai portoenterostomy may explain why age is a major determinant of survival of the native liver. Blinded fibrosis scoring of surgical liver biopsies demonstrated that age and fibrosis correlate. Those biopsies with severe fibrosis predicted significantly worse survival.

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