Endothelin and vascular function in liver disease.
review · Level V
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- Record sourced from PubMed, PMID 14724140.
- Also identified by PMC identifier 1774918.
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Abstract
The endothelins are a group of three related peptides with two receptor subtypes, ET(A) and ET(B). Following the discovery of endothelin 1 as a potent vasoconstrictor, there has been intense interest in the role of endothelin on vascular function in liver disease. Speculation on the role of endothelin in the pathogenesis of acute renal failure, including hepatorenal syndrome, has also been speculated.
Medical subject headings
- Endothelins
- Liver Cirrhosis
- Muscle, Smooth, Vascular