Drug immunosuppression therapy for adult heart transplantation. Part 2: clinical applications and results.
review · Level V
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Abstract
This review describes the clinical application of classical immunosuppressive drugs as well as that of more recent drugs. All current immunosuppressive drugs target T-cell activation, and cytokine production and clonal expansion, or both. Immunosuppressive protocols can be broadly divided into induction therapy, maintenance immunosuppression, and treatment of acute rejection episodes.
Medical subject headings
- Heart Transplantation
- Immunosuppression Therapy
- Immunosuppressive Agents
- Transplantation Immunology