Analyzing sleep abnormalities in HIV-infected patients treated with Efavirenz.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 14727217.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Ambulatory electroencephalogram monitoring was performed for 18 HIV-infected subjects treated with efavirenz with and without insomnia and for 13 healthy control subjects. All patients receiving efavirenz had longer sleep latencies and shorter duration of deep sleep, although poor sleepers also showed reduced sleep efficiency and shorter duration of rapid eye movement sleep. Efavirenz plasma levels were higher in patients with insomnia and/or reduced sleep efficiency.
Medical subject headings
- Oxazines
- Reverse Transcriptase Inhibitors
- Sleep Initiation and Maintenance Disorders
- Sleep Stages