ROSO: optimizing oligonucleotide probes for microarrays.
other · Level V
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- Record sourced from PubMed, PMID 14734320.
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Abstract
ROSO is software to design optimal oligonucleotide probe sets for microarrays. Selected probes show no significant cross-hybridization, no stable secondary structures and their Tm are chosen to minimize the Tm variability of the probe set. The program is available on the internet. Sources are freely available, for non-profit use, on request to the authors. http://pbil.univ-lyon1.fr/roso
Medical subject headings
- Algorithms
- Computer-Aided Design
- Oligonucleotide Array Sequence Analysis
- Oligonucleotide Probes
- Oligonucleotides
- Software