Reversible language regression as an adverse effect of topiramate treatment in children.

Gross-Tsur, Varda; Shalev, Ruth S · Neurology · 2004

case_series · Level IV

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Abstract

Profound language regression developed in three children with epilepsy 4 to 28 weeks after beginning topiramate (TPM). TPM was administered as an adjunctive antiepileptic drug at doses of 2.5 to 6.0 mg/kg/day. Language functions recovered while TPM was being reduced in dose or stopped.

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