Gene Unscrambler for detangling scrambled genes in ciliates.
basic_science · Level V
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- Record sourced from PubMed, PMID 14751966.
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Abstract
Scrambled genes are surprisingly common in some species of ciliates. Until now there was no software available to analyze automatically these genes. We present here a program that can automatically align the macronuclear and micronuclear forms of a gene, outputting the location of the macronuclear destined segments and pointer sequences. A web version of the program is available free of charge and can be accessed at http://oxytricha.princeton.edu/GeneUnscrambler.htm
Medical subject headings
- Cell Nucleus
- Chromosome Mapping
- Ciliophora
- Sequence Alignment
- Sequence Analysis, DNA
- Software
- User-Computer Interface